Quick Answer: Why Are My Titers Negative?

What does a titer blood test show?

A titer test is a laboratory blood test.

It checks for the presence of certain antibodies in the blood stream.

Testing involves drawing blood from a patient and check it in a lab for presence of bacteria or disease.

It is often used to see if someone is immune to a certain virus or needs vaccination..

What is the purpose of an antibody titer?

The antibody titer is a test that detects the presence and measures the amount of antibodies within a person’s blood. The amount and diversity of antibodies correlates to the strength of the body’s immune response.

What happens if varicella titer is negative?

If you have a negative or indeterminate titer, obtain one dose of varicella vaccine and repeat titer in 4-6 weeks. If titer is still negative, contact Student Health. Vaccine doses must be at least 28 days apart.

Do varicella titers want positive or negative?

A positive IgG result coupled with a negative IgM result indicates previous vaccination to or infection with VZV. These individuals are considered to have protective immunity to reinfection. A negative IgG result coupled with a negative IgM result indicates the absence of prior exposure to VZV and nonimmunity.

What does a titer test show?

A titer is a laboratory test that measures the presence and amount of antibodies in blood. A titer may be used to prove immunity to disease. A blood sample is taken and tested. If the test is positive (above a particular known value) the individual has immunity.

What is a high antibody titer?

The greater the concentration of the specific antibody in the serum sample, the higher the titer. For example, a titer for an influenza hemagglutination inhibition assay of 1:10 would be very low; a titer of 1:320 would be high. A low or undetectable titer indicates very little antibody present in the serum.

Do titers prove immunity?

Serum titers are blood tests that measure whether or not you are immune to a given disease(s). More specifically a quantitative serum titer is a titer with a numerical value indicating your actual degree of immunity to a disease(s).

Why is my varicella titer negative?

What does a negative VZV IgG result mean in a patient who has been vaccinated? A negative result may or may not be consistent with a lack of immunity to VZV and is therefore uninformative. Vaccinated individuals generally have a lower level of VZV antibodies than do patients with a history of infection.

Are titers accurate?

Titers may not be totally accurate: The titer test was developed based on the level of measles antibodies in the blood of patients who’d been exposed to measles naturally—by being exposed to the disease itself.

How often should MMR titers be checked?

Measles/Mumps/Rubella Those who have had only 1 documented dose of the MMR vaccine should receive a second dose to complete the initial series. Serologic testing for immunity should be obtained at least 1 month after the second dose. Vaccination series need not be repeated if there is documentation.

How often should titers be checked?

A new titer should be drawn 3-4 weeks after this booster. If MMR has been given, the recommendation is to wait 4-6 weeks before giving a routine TB PPD skin test.